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University Health Network’s (UHN) office of Technology Development & Commercialization (TDC) works with inventors at UHN to drive the most promising discoveries forward to patient impact through commercialization. UHN is Canada’s largest research hospital. Our five research institutes and four hospitals are home to approximately 837 researchers, as well as their staff and students, and our annual research funding currently exceeds CAD $330 million.

The four hospitals of UHN – Toronto Western Hospital, Toronto General Hospital, Toronto Rehab Institute and Princess Margaret Cancer Centre – share a long and storied history of transforming health care in their local communities, across Canada and around the world. High-impact examples from UHN hospitals include the discovery of insulin, the use of radiation to treat cancer, the identification of stem cells, and more recently, advances in image-guided radiation therapy.

Our office works with investigators in each of the following UHN research institutes:

Princess Margaret Cancer Centre

Princess Margaret Cancer Centre

Cancer research is the priority at the Princess Margaret (PM) Cancer Centre, one of the University Health Network’s five research institutes. Researchers here employ state-of-the-art tools in genomics, proteomics, structural biology, molecular biology, biophysics and the behavioural sciences.

With these tools UHN researchers analyze cancerous cells at the molecular level; test gene and cellular therapies for cancer and other diseases; develop new technologies for diagnosing and treating cancer; determine the effects of diet and behaviour on cancer risks; and develop and test informatics tools for the large-scale analysis of patient populations.

The Campbell Family Cancer Research Institute

The newest addition to the PM Cancer Centre, this institute will accelerate the pace of breakthrough cancer research, facilitating the translation of cancer discoveries into new life-saving therapies and more personalized cancer treatments for each patient.

The Campbell Family Institute for Breast Cancer Research

Recognizing the need to combat the most common cancer in Canadian women, this institute focuses on developing the next generation of treatments for breast cancer patients. Led by internationally recognized scientists Drs. Tak Mak and Pamela Ohashi, The Campbell Family Institute for Breast Cancer Research joins together basic, translational and clinical research and will focus on developing new drugs and therapies that are more effective, less toxic and can increase a patient’s quality and length of life.

Toronto General Research Institute

Toronto General Research Institute
Located at Toronto General Hospital

The Toronto General Research Institute (TGRI) is the research arm of the Toronto General Hospital.

Toronto General Hospital is well-known for its excellent clinical care and it is important to recognize that ground-breaking research efforts underlie our surgical and medical innovations. TGRI’s research program encompasses research in cardiology, transplantation, immunology and autoimmunity, infectious diseases, tissue injury and diabetes. Building upon this work, scientists are able to develop improved methods of treatment and cure.

Organ transplants, cardiac pacemakers, novel therapies for endocrine and autoimmune disorders—all are based upon research carried out in TGRI’s laboratories and clinics.

Toronto Western Research Institute

Toronto Western Research Institute
Located at Toronto Western Hospital

One of the five research institutes of UHN, Toronto Western Research Institute (TWRI) is home to the research programs associated with the neural and visual sciences, musculoskeletal disease and urban and community health priority programs. TWRI Neuroscientists explore the function of the nervous system as they develop treatments for spinal cord injuries, cerebral ischemia, vascular malformations, brain tumours, neurophthalmologic disorders and neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease.

TWRI is also home to the Vision Science Research Program, a joint UHN/University of Toronto Program. The Program’s research is directed to the following areas: molecular genetics of blinding eye diseases and brain disorders; treatment, biophysics and psychophysics of glaucoma; eye movement control mechanisms; neuronal damage; retinal degeneration and diabetic retinopathy.

Arthritis and associated degenerative diseases are the focus of the researchers in the musculoskeletal research program. Their investigations are aimed at revealing the causes of, and generating therapies for, these ailments.

TWRI researchers associated with the Healthy Connections program are seeking solutions to public and community health concerns. Toronto Western Hospital serves clients from culturally and economically diverse backgrounds. At TWRI, they devise and study methods of education, prevention, health promotion and health care delivery in order to better serve this population.

Techna Institute

Banting Building Techna Institute
Located at the Banting Building

Created in collaboration with the University of Toronto, Techna is a new research institute at UHN devoted to the advancement of medical health device technologies. The Techna mission is twofold: to shorten the time interval from technology discovery and development to application of such technologies for the benefit of patients and the health care system, and to facilitate the convergence of basic investigation, technology development and translational research.

For more information, please visit the Techna webpage

Toronto Rehabilitation Institute

TRI Toronto Rehabilitation Institute
Located at Toronto Rehab

As the research institute associated with Toronto Rehab, the Toronto Rehabilitation Institute (TRI), is one of the most technologically advanced rehabilitation research centres in the world. It is dedicated to revolutionizing rehabilitation and maximizing life for people living with the effects of disability, illness and aging–and to preventing injury by making homes, streets and workplaces safer.

Toronto Rehab’s broad program of research involves:

developing treatments and technologies to prevent injury and illness, and restore function to a high level enhancing quality of life, participation and productivity facilitating a quicker return to the community and work modifying the environment to improve accessibility developing technologies to allow people to remain safely in their own homes assisting professional and family caregivers, and reducing their injuries increasing accessibility, effectiveness and efficiency of the healthcare system

iDAPT Centre for Rehabilitation Research
CEAL_extThe iDAPT Centre for Rehabilitation Research is a unique, newly minted network of facilities where ideas can be cultivated and tested in a real-life setting, leading to practical new therapies and assistive devices to enhance the lives of older people and those with disabling injury or illness.

Located in the heart of Canada’s ‘Discovery District’ in downtown Toronto, the iDAPT Centre consists of 15 cutting-edge labs, workshops, and other research spaces. Built in collaboration with the University of Toronto, it features an underground lab with a motion simulator that can recreate different environments, such as winter blizzards, slopes and busy streets. iDAPT researchers team up with investigators from top academic institutions in Canada, the U.S., and throughout the world. Scientists work alongside clinicians, students, consumers, engineers, industrial designers and in partnership with industry.

Nine Research Areas
Toronto Rehab Institute scientists come from a wide range of disciplines and conduct research in nine key areas:

  • Artificial Intelligence and Robotics
  • Cardiopulmonary Fitness
  • Cognition
  • Communication
  • Mobility
  • Neural Engineering and Therapeutics
  • Optimization of the Rehabilitation System
  • Sleep and Upper Airway
  • Technology


Toronto Rehab Institute researchers work to move research findings into practice and ideas into marketable products so that people can benefit. Its scientists work closely with clinicians, policy makers, entrepreneurs and others to translate our discoveries into action. Toronto Rehab’s industry-friendly Club program and state-of-the-art design and prototyping facilities help to accelerate the movement of products into the marketplace.

For more information, please visit the TRI’s webpage